주식회사 태연이엔지


	This is a closed room in which temperature, humidity, oxygen ratio, illumination intensity as well as floating dust are environmentally controlled. In particular, clean room creates airflow free from turbulence by inducing massive clean airflow, and then quickly discharging indoor dust.

For more efficient use and maintenance of the clean room, following four principles must be followed.

1) Minimize the inflow of dust and particles from outdoors.
2) Prevent dust and particles from entering the room.
3) Minimize dust and particles caused by indoor equipment and personnel.
4) Prevent dust and particles from accumulating.

There are two types of clean room: Industrial Clean Room (ICR) for industrial purposes, and Bio Clean Room (BCR) for hospitals, pharmacies, food producers, and sterilized labs.
More specifically, bio clean room can be classified into GMP (pharmaceutical sector) and GLP (animal lab).

◈ Industrial Clean Room

ICR facility can be used to remove radioactive particles in nuclear plants. The clean room came into being due to the precision and electronic industries, which needed to remove the dust that affects products.

Now, the clean room is widely used, not only for the IC industry, but for film production, printing, coating, chemical and medicine production processes.

In the process of producing tiny semiconductors, such as VISI, even the dust smaller than 0.1μ needs to be removed to prevent air contamination. This kind of system is dubbed "Super Clean Room" and gaining popularity.

◈ Bio Clean Room

While the ICR is to remove micro particles such as dust, the Biological Clean Room is to control microorganisms.

BCR was developed due to the necessity of sterilized operation rooms. Now, it is used for laboratory animal facility, medicine production, bioengineering, food engineering and space development to control cleanness, temperature and humidity.

◈ What is GMP?

Good Manufacturing Practice (GMP) are basic conditions to guarantee safety and effectiveness in terms of quality, meaning manufacturing and managing the standard of quality medicines.

These are detailed standards to produce high quality medicines, regulating material warehousing down to final delivery. Through modernized and automated production facilities, and careful process management, this standard is in place to minimize man-made errors, and produce high quality medicine with greater safety. The GMP regime was installed by the U.S in 1963, and came into effect in 1964. South Korea set up this regime in 1977 and has recommended voluntary implementation to industries.

◈ What is GLP?

Good Laboratory Practice is to guarantee the credibility of various toxicity tests that are performed to assess safety of medicine and cosmetics. This standard is for systematic and organizational management of the whole test, including researchers, experimental facilities and equipment and test method.

◈ What is Bio-Hazard?

The Biohazard Prevention facility is to prevent pollutants from spreading outside. In contrast with clean room, it installs a HEPA filter at the exhaustion side, and turns indoor pressure negative. This facility, equipped with safety cabinets and isolators, is likely to be widely used for the purpose of genetic experiments with the development of genetic engineering.

◈ Clean Room Type

1. LAMINAR FLOW

	Turning indoor airflow to piston flow can prevent the pollution source from spreading while making exhaustion easier.
	≫ Down Air Flow Type ;
	Airflows send clean air from the ceiling to the floor, which helps dust caused by work to be instantaneously absorbed by the floor, making indoor air cleaner. Airflow velocity should be around 0.3~0.5m/sec.
	≫ Cross Air Flow Type ;
	This type cleanroom forces air flow from one wall to its oppsite side wall. One of the features of this type is that lower side is less clean due to influence from upper operation. Through this method, you can achieve upper cleanliness level of Class 100 or less, and the lower level of Class 1000, depending on the upper operation contents. Unloading velocity is higher than 0.5m/sec.

2. TURBULENT FLOW

This dilution method is to increase the cleanliness level by attaching a HEPA filter at the air-conditioner diffusers, and diluting indoor pollution sources with clean diffused air.

The achievable cleanliness level is around 1,000 to 100,000. Ventilation frequency is 20 to 80 times per HR. Even if you raise the ventilation frequency to 80 or more (for example, 100 times per HR), the cleanliness level improvement rate is not proportional.